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唑来膦酸单水合物

Zoledronic Acid Monohydrate （订货以英文为准）

编号：Z140117
CAS号：165800-06-6
分子式：C5H12N2O8P2
分子量：290.10
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Z140117-5g 阿拉丁 5g ¥500.90
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Z140117-1g 阿拉丁 1g ¥164.90
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Z140117-25g 阿拉丁 25g ¥1899.90
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产品名称 Zoledronic Acid Monohydrate
中文名称 唑来膦酸单水合物
CAS号 165800-06-6
分子式（M.F.） C5H12N2O8P2
分子量（M.W.） 290.10
储存条件 避光;室温
敏感性对热、湿度和光线敏感
溶解性Soluble in water (7 mg/ml), 0.1N NaOH, methanol (0.12 mg/ml at 25 °C), and ethanol (0.13 mg/ml at 25 °C).
存贮条件储存温度2-8°C
应用A highly potent bisphosphonate and activator of PKC.
产品介绍Zoledronic acid(CGP 42446; ZOL 446)一水合物是PKC活化剂，能诱导多发性骨髓瘤细胞系凋亡和抑制hFOB细胞增殖。
生化机理Zoledronic acid monohydrate, also known as cgp 42'446, is a heterocyclic bisphosphonate that is considered to have the highest potency of bisphosphonates for suppression of increased bone resorption and has been used in several osteoporosis studies. The compound has been observed to be more effective than pamidronate. Zoledronic acid has been used in studies investigating mesothelioma. Zoledronic acid monohydrate is an inhibitor of ASM and FDPS and an activator of PKC.
别名唑来膦酸单水合物;唑来磷酸一水化合物;1-羟基-2-(1-咪唑基)乙烷-1,1-二磷酸P,P′-[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid monohydrate;Zoledronate monohydrate;[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate;1-Hydroxy-2-(1-imidazolyl)ethane-1,1-diphosphonic Acid Monohydrate;CGP 42446 monohydrate;CGP42446A monohydrate;ZOL 446 monohydrate
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