| 熔点 | 196.5-198.5 °C |
| 溶解性 | Soluble in water (5 mg/ml), DMSO (92 mg/ml), and ethanol (20 mg/ml). |
| 存贮条件 | 储存温度2-8°C |
| 应用 | A SR-1A agonist and a selective α1D-AR antagonist. |
| 产品介绍 | BMY 7378是一种多靶点抑制剂，作用于α2C-adrenoceptor和α1D-adrenoceptor，pKi分别为6.54和8.2，且为混合型5-HT1A受体激动剂和拮抗剂，pKi为8.3。 |
| 备注 | BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3 |
| 生化机理 | BMY 7378 dihydrochloride is a putative SR-1A (5-HT1A) partial agonist, and high affinity α1D-AR adrenoceptor antagonist. |
| 别名 | 8-[2-[4-(2-甲氧基苯基)-1-哌嗪基]乙基]-8-氮杂螺[4.5]癸烷-7,9-二酮盐酸盐;BMY 7378; 8-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione dihydrochloride;N-(2-(4-(o-Methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimide dihydrochloride;BMY 7378 |
BMY 7378 二盐酸盐
BMY 7378 dihydrochloride （订货以英文为准）
编号：B129688
CAS号：21102-95-4
| 产品名称 | BMY 7378 dihydrochloride |
| 中文名称 | BMY 7378 二盐酸盐 |
| CAS号 | 21102-95-4 |
| 储存条件 | 2-8°C储存 |
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