溶解性 | DMSO 3 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度-20°C |
备注 | CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 μM, 0.198 μM and 0.227 μM, respectively. It is less potent to FGFR3, GSK3β, PDGFRβ, etc. |
生化机理 | CCT129202 is a Aurora kinase inhibitor with IC50 of 0.042 ± 0.022, 0.198 ± 0.05, and 0.227 ± 0.064 μmol/L for Aurora A, Aurora B, and Aurora C, respectively. |
别名 | 2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)-N-(thiazol-2-yl)acetamide;2-(4-(6-chloro-2-(4-(dimethylamino)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)-N-(thiazol-2-yl)acetamide |
CCT129202
CCT129202 (订货以英文为准)
编号:C127546
CAS号:942947-93-5
分子式:C23H25CLN8OS
分子量:497.02
产品名称 | CCT129202 |
中文名称 | CCT129202 |
CAS号 | 942947-93-5 |
分子式(M.F.) | C23H25CLN8OS |
分子量(M.W.) | 497.02 |
储存条件 | -20°C储存 |
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