NBD-556,CD4类似物

NBD-556 (订货以英文为准)

编号:N125945
CAS号:333353-44-9
分子式:337.84
货号 品牌 包装 目录价 您的价格 库存 数量 购买
N125945-25mg 阿拉丁 25mg ¥791.90
N125945-5mg 阿拉丁 5mg ¥175.90
N125945-100mg 阿拉丁 100mg ¥1482.90
产品名称 NBD-556
中文名称 NBD-556,CD4类似物
CAS号 333353-44-9
分子式(M.F.) 337.84
储存条件 -20°C储存
溶解性DMSO
存贮条件储存温度-20°C
产品介绍NBD-556是CD4的小分子模拟物,能识别HIV-1包膜蛋白gp120。
生化机理NBD-556 N-phenyl-N′-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamide analogs as a novel class of human immunodeficiency virus type 1 (HIV-1) entry inhibitors that block the gp120–CD4 interaction. Human immunodeficiency virus (HIV-1) interaction with the primary receptor, CD4, induces conformational changes in the viral envelope glycoproteins that allow binding to the CCR5 second receptor and virus entry into the host cell. The small molecule NBD-556 mimics CD4 by binding the gp120 exterior envelope glycoprotein, moderately inhibiting virus entry into CD4-expressing target cells and enhancing CCR5 binding and virus entry into CCR5-expressing cells lacking CD4.
别名NBD 556;NBD556;N-(4-氯苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺;N1-(4-氯苯基)-N2-(2,2,6,6-四甲基-4-哌啶基)乙二酰胺;N1-(4-氯苯基)-N2-(2,2,6,6-四甲基哌啶-4-基)草酰胺;NBD 556;NBD556;N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide;N-(4-Chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide;N1-(4-Chlorophenyl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide
标识符号https://www.aladdin-e.com/images/ghs/ghs06.jpg
信号词Danger
危害声明H301-H315-H319-H335
警示性声明P261-P301 + P310-P305 + P351 + P338
个人防护设备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECSUE7570000
WGK德国3
搜索质检报告(COA)
搜索MSDS
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