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2-(2,6-二氯苯氨基)苯乙酸

Diclofenac （订货以英文为准）

编号：D155733
CAS号：15307-86-5
分子式：C14H11CL2NO2
分子量：296.15
货号 品牌 包装 目录价 您的价格 库存 数量 购买
D155733-25g 阿拉丁 25g ¥72.90
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D155733-5g 阿拉丁 5g ¥44.90
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D155733-100g 阿拉丁 100g ¥195.90
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D155733-1g 阿拉丁 1g ¥36.90
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D155733-500g 阿拉丁 500g ¥667.90
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产品名称 Diclofenac
中文名称 2-(2,6-二氯苯氨基)苯乙酸
CAS号 15307-86-5
分子式（M.F.） C14H11CL2NO2
分子量（M.W.） 296.15
储存条件 2-8°C储存
熔点158°C
存贮条件储存温度2-8°C
应用Diclofenac (双氯芬酸) 是COX抑制剂，对绵羊的COX-1和-2的IC50分别为60和220 nM。
产品介绍Diclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Target: COX Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. The primary mechanism responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). It also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Inhibition of COX also decreases prostaglandins in the epithelium of the stomach, making it more sensitive to corrosion by gastric acid. This is also the main side effect of diclofenac. Diclofenac has a low to moderate preference to block the COX2-isoenzyme and is said to have, therefore, a somewhat lower incidence of gastrointestinal complaints than noted with indomethacin and aspirin.
别名双氯芬酸;2-(2,6-二氯苯氨基)苯乙酸;2-[(2,6-二氯苯基)氨基]-苯乙酸;奥尔芬;2-(2,6-Dichloroanilino)phenylacetic Acid
Merck Index2801
标识符号https://www.aladdin-e.com/images/ghs/ghs07.jpg
信号词Warning
危害声明H315,H319
警示性声明P305+P351+P338
个人防护设备dust mask type N95 (US),Eyeshields,Gloves
RTECSDJ3100040
WGK德国3
风险声明 (欧洲)36/38
安全声明（欧洲）24,26
危害码（欧洲）Xi
搜索质检报告(COA)
搜索MSDS
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