熔点 | 360°C |
应用 | 抗肿瘤。 |
产品介绍 | 6-Thioguanine is a chemotherapy drug that demonstrates immunosuppressive, anti-neoplastic, and anti-cancer activities. This chemical is often used to treat leukemia and inflammatory diseases. Chemical produces dose-dependent inhibition of stimulated expression of TRAIL protein. |
生化机理 | Antimetabolite used in the treatment of leukemias. Competes with hypoxanthine and guanine for the enzyme hypoxanthine-guanine phosphoribosyltransferase, which catalzyes a critical step in the generation of purine nucleotides.Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia. |
别名 | 2-氨基-6-巯基嘌呤; 6-硫代鸟嘌呤; 2-氨基-6-巯嘌呤;2-Amino-6-mercaptopurine; 2-Amino-6-purinethiol; 6-Mercaptoguanine |
6-硫鸟嘌呤
6-Thioguanine (订货以英文为准)
编号:T106639
CAS号:154-42-7
分子式:C5H5N5S
分子量:167.19
产品名称 | 6-Thioguanine |
中文名称 | 6-硫鸟嘌呤 |
CAS号 | 154-42-7 |
分子式(M.F.) | C5H5N5S |
分子量(M.W.) | 167.19 |
Merck Index | 4391 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H302 |
个人防护设备 | Eyeshields,Faceshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
RTECS | NR2392000 |
WGK德国 | 3 |
安全声明(欧洲) | S24/25; |
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