别名 | ;['3,6-Bis(4-pyridyl)-1,2,4,5-tetrazine'] |
3,6-二(4-吡啶基)-1,2,4,5-四嗪
3,6-Di(4-pyridyl)-1,2,4,5-tetrazine (订货以英文为准)
编号:D155261
CAS号:57654-36-1
分子式:C12H8N6
分子量:236.23
产品名称 | 3,6-Di(4-pyridyl)-1,2,4,5-tetrazine |
中文名称 | 3,6-二(4-吡啶基)-1,2,4,5-四嗪 |
CAS号 | 57654-36-1 |
分子式(M.F.) | C12H8N6 |
分子量(M.W.) | 236.23 |
储存条件 | 2-8°C储存 |
Reaxys-RN | 113297 |
RTECS | DW1758000 |
技术规格
Background: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. |
Applications: | WB, IHC |
Name of antibody: | HDAC5 |
Immunogen: | Synthetic peptide of human HDAC5(Ab-498) |
Full name: | histone deacetylase 5 |
Synonyms: | HD5; NY-CO-9 |
SwissProt: | Q9UQL6 |
IHC positive control: | Human breast carcinoma |
IHC Recommend dilution: | 50-100 |
WB Predicted band size: | 122 kDa |
WB Positive control: | 293 and HepG2 cells |
WB Recommended dilution: | 500-1000 |
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