| 溶解性 | DMSO 40 mg/mL Water <1 mg/mL Ethanol 30 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | KU-60019是KU-55933的改良类似物，对ATM的IC50为6.3 nM。 |
| 生化机理 | KU-60019 is a potent inhitor of ATM (ataxia telangiectasia mutated) kinase, a member of phosphatidylinositol-3-kinase-related kinase family that is critical in regulating cell cycle checkpoints and DNA repair. KU-60019 has an IC50 value of 6.3 nM. KU-60019 radiosensitizes U1242 human glioma cells, and also blocks U1242 cell migration and invasion through matrigel. |
| 别名 | KU60019;KU 60019；(2R,6S)-2,6-二甲基-N-[5-[6-(4-吗啉基)-4-氧代-4H-吡喃-2-基]-9H-噻吨-2-基]-4-吗啉乙酰胺;KU60019;KU 60019； (2R,6S)-2,6-Dimethyl-N-[5-[6-(4-morpholinyl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl]-4-morpholineacetamide |
KU-60019,ATM激酶抑制剂
KU-60019 （订货以英文为准）
编号：K127121
CAS号：925701-49-1
分子式：C30H33N3O5S
分子量：547.67
| 产品名称 | KU-60019 |
| 中文名称 | KU-60019,ATM激酶抑制剂 |
| CAS号 | 925701-49-1 |
| 分子式（M.F.） | C30H33N3O5S |
| 分子量（M.W.） | 547.67 |
| 储存条件 | -20°C储存 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
| 信号词 | Danger |
| 危害声明 | H315,H319,H334,H335 |
| 警示性声明 | P261,P305+P351+P338,P342+P311 |
| 个人防护设备 | dust mask type N95 (US),Eyeshields,Faceshields,Gloves |
| WGK德国 | 3 |
| 安全声明（欧洲） | 22,24/25 |
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