| 溶解性 | 25°C: DMSO |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | JNK-IN-7是 JNK1，2，3抑制剂，IC50分别为1.54，1.99，0.75 nM，还能结合IRAK1，PIK3C3，PIP5K3和PIP4K2C。 |
| 生化机理 | Covalent modification of IRAK1 by JNK-IN-7 is a possibility and subsequent biochemical kinase assay revealed anIC50 of ~10 nM against IRAK1. JNK-IN-7 exhibited binding inhibition of 95% or more to approximately 14 kinases at the concentration of 1.0 μM. JNK-IN-7 was next tested for its ability to inhibit the enzymatic activity of a panel of 121 kinases at a concentration of 1.0 μM |
| 别名 | JNK inhibitor;3-((4-(二甲基氨基)-1-氧代-2-丁烯-1-基)氨基)-N-(4-((4-(3-吡啶基)-2-嘧啶基)氨基)苯基)苯甲酰胺;;JNK inhibitor;3-((4-(dimethylamino)-1-oxo-2-buten-1-yl)amino)-n-(4-((4-(3-pyridinyl)-2-pyrimidinyl)amino)phenyl)benzamide |
JNK-IN-7
JNK-IN-7 （订货以英文为准）
编号：J124921
CAS号：1408064-71-0
分子式：C28H27N7O2
分子量：493.56
| 产品名称 | JNK-IN-7 |
| 中文名称 | JNK-IN-7 |
| CAS号 | 1408064-71-0 |
| 分子式（M.F.） | C28H27N7O2 |
| 分子量（M.W.） | 493.56 |
| 储存条件 | -20°C储存 |
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