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BML-190,CB 2受体反向激动剂

BML-190 （订货以英文为准）

编号：B126713
CAS号：2854-32-2
分子式：C23H23N2O4CL
分子量：426.89
货号 品牌 包装 目录价 您的价格 库存 数量 购买
B126713-50mg 阿拉丁 50mg ¥792.90
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B126713-10mg 阿拉丁 10mg ¥259.90
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B126713-1mg 阿拉丁 1mg ¥92.00
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B126713-250mg 阿拉丁 250mg ¥1237.90
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B126713-100mg 阿拉丁 100mg ¥800.90
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B126713-25mg 阿拉丁 25mg ¥499.90
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产品名称 BML-190
中文名称 BML-190,CB 2受体反向激动剂
CAS号 2854-32-2
分子式（M.F.） C23H23N2O4CL
分子量（M.W.） 426.89
储存条件 -20°C储存
溶解性DMSO 22 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件储存温度-20°C
备注BML-190 is a selective cannabinoid CB2 receptor inverse agonist with Ki of 435 nM, with 50-fold selectivity over CB1 receptor.
生化机理BML-190 is a potent and selective CB2 receptor ligand (Ki values are 435 nM and > 2 μM for CB2 and CB1 respectively). Studies involving HEK-293 cells indicate that BML-190 increases the accumulation of cAMP, via forskolin-stimulated mechanism. Alternate studies suggest that BML-190 reduces the toxicity of culture supernatants to SH-SY5Y human neutroblastoma cells. Various research suggests that BML-190 is an essential tool in studying the proliferation of neuroblastoma.
别名Indomethacin Morpholinylamide;Ethanone, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-;Indomethacin Morpholinylamide;Ethanone, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-
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