溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
产品介绍 | RG1678 (Bitopertin)是非竞争性甘氨酸重吸收(GlyT1)抑制剂。 |
生化机理 | RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1). Recent Phase II data shows that RG1678 is effective in reducing the negative symptoms when given in combination with second generation antipsychotics. RG1678 is currently in Phase III trials for the treatment of the negative symptoms of schizophrenia. |
别名 | RG1678;RO4917838;RG-1678;RG 1678;RO-4917838;RO 4917838;比拓喷丁;(S)-[4-(3-氟-5-三氟甲基吡啶-2-基)哌嗪-1-基][5-(甲磺酰基)-2-(2,2,2-三氟-1-甲基乙氧基)苯基]甲酮;RG1678;RO4917838;RG-1678;RG 1678;RO-4917838;RO 4917838;Paliflutine;(S)-[4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-(methanesulfonyl)-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]methanone; [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-Methylsulfonyl-2-[((S)-2,2,2-trifluoro-1-methylethyl)oxy]phenyl]methanone |
Bitopertin,非竞争性抑制剂
Bitopertin (订货以英文为准)
编号:B127005
CAS号:845614-11-1
分子式:C21H20F7N3O4S
分子量:543.46
产品名称 | Bitopertin |
中文名称 | Bitopertin,非竞争性抑制剂 |
CAS号 | 845614-11-1 |
分子式(M.F.) | C21H20F7N3O4S |
分子量(M.W.) | 543.46 |
储存条件 | -20°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H315-H319-H335 |
警示性声明 | P261-P305 + P351 + P338 |
个人防护设备 | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
WGK德国 | 3 |
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