溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
生化机理 | Calcitonin gene-related peptide (CGRP) is closely involved in the cascade of molecular events leading to migraine painful crisis. New CGRP-R antagonist, such as BMS-927711, is in the pipeline and its developments will outline the future of this drug class. BMS-927711 has good oral bioavailability in rat and cynomolgus monkey, attractive overall preclinical properties, and shows dose-dependent activity in a primate model of CGRP-induced facial blood flow. BMS-927711 is presently in phase II clinical trials. |
BMS-927711,CGRP受体拮抗剂
BMS-927711 (订货以英文为准)
编号:B125641
CAS号:1289023-67-1
分子式:C28H28F2N6O3
分子量:534.56
产品名称 | BMS-927711 |
中文名称 | BMS-927711,CGRP受体拮抗剂 |
CAS号 | 1289023-67-1 |
分子式(M.F.) | C28H28F2N6O3 |
分子量(M.W.) | 534.56 |
储存条件 | 避光;-20°C储存 |
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