溶解性 | DMSO 86 mg/mL Water 5 mg/mL Ethanol 1 mg/mL |
存贮条件 | 储存温度-20°C |
应用 | A selective receptor agonist for the δ-opioid receptor |
产品介绍 | ADL5859是δ-阿片受体选择性激动剂,Ki为0.8 nM,对hERG有弱抑制性。 |
备注 | ADL5859 HCl is a δ-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor κ, μ, and weak inhibitory activity at the hERG channel. Phase 2. |
生化机理 | ADL-5859 (ADL5859) is an δ-opioid receptor agonist (Ki=0.84 nM, EC50=20 nM). ADL-5859 (ADL5859) is an agonist agent that selectively stimulates the δ-opioid receptor with potential application in a wide range of inflammatory, neuropathic and acute pain conditions. In addition, Delta agonists are thought to modulate other biological processes that may manifest themselves in disease states or conditions such as overactive bladder and depression.ADL-5859 (ADL5859) is useful for inflammatory, neuropathic and acute pain conditions. |
别名 | ADL5859; ADL 5859; N,N-二乙基-4-(5-羟基螺(2H-1-苯并吡喃-2,4'-哌啶)-4-基)苯甲酰胺盐酸盐;;ADL5859; ADL 5859;N,N-Diethyl-4-(5-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-4-yl)benzamide hydrochloride; |
ADL5859 盐酸盐
ADL5859 HCl (订货以英文为准)
编号:A127848
CAS号:850173-95-4
分子式:C24H28N2O3.HCL
分子量:428.96
产品名称 | ADL5859 HCl |
中文名称 | ADL5859 盐酸盐 |
CAS号 | 850173-95-4 |
分子式(M.F.) | C24H28N2O3.HCL |
分子量(M.W.) | 428.96 |
储存条件 | -20°C储存 |
信号词 | Warning |
危害声明 | H302-H315-H317-H319-H335 |
警示性声明 | P261-P280-P305 + P351 + P338 |
RTECS | GP4250000 |
WGK德国 | 3 |
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