| 沸点 | 145°C |
| 熔点 | 7-10°C |
| 折光率 | 1.471 |
| 溶解性 | Soluble in water and most organic solvents, Soluble in water and most organic solvents |
| 应用 | As as stabilizer in chlorinated organics, and as a catalyst for condensation reactions. |
| 别名 | 二醋酸二丁基锡;二正丁基二乙酸锡;Di-n-butyltin diacetate |
二乙酸二丁基锡
Dibutyltin Diacetate （订货以英文为准）
编号：D155023
CAS号：1067-33-0
分子式：C12H24O4SN
分子量：351.02
| 产品名称 | Dibutyltin Diacetate |
| 中文名称 | 二乙酸二丁基锡 |
| CAS号 | 1067-33-0 |
| 分子式（M.F.） | C12H24O4SN |
| 分子量（M.W.） | 351.02 |
| 储存条件 | 充氩 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs09.jpg |
| 信号词 | Warning |
| 危害声明 | H302;H315;H319;H400 |
| 警示性声明 | P273;P280;P301;P312;P330;P305;P351;P338;P337;P313;P391 |
| RTECS | AZ0883332 |
| 风险声明 (欧洲) | R22;R36/38;R50 |
| 安全声明（欧洲） | S26;S61 |
| 危害码（欧洲） | Xn,N |
技术规格
| Background: | Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor suppressor function. Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation. Dephosphorylates tyrosine-phosphorylated focal adhesion kinase and inhibits cell migration and integrin-mediated cell spreading and focal adhesion formation. May be a negative regulator of insulin signaling and glucose metabolism in adipose tissue. |
| Applications: | WB, IHC, IF |
| Name of antibody: | PTEN (Phospho-Ser380/Thr382/Thr383) |
| Immunogen: | Synthetic peptide of human PTEN (Phospho-Ser380/Thr382/Thr383) |
| Full name: | phosphatase and tensin homolog (Phospho-Ser380/Thr382/Thr383) |
| Synonyms： | BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del |
| SwissProt: | P60484 |
| IHC positive control: | Human breast carcinoma |
| IHC Recommend dilution: | 50-100 |
| WB Predicted band size: | 54 kDa |
| WB Positive control: | Hela cells |
| WB Recommended dilution: | 500-1000 |
| IF Positive control: | Hela cells |
| IF Recommended dilution | 100-200 |
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