沸点 | 251.8° C |
熔点 | 210° C |
折光率 | 1.53 |
旋光率 | -63o |
溶解性 | Soluble in water (30 mg/ml at 25° C), ethanol (<1 mg/ml at 25° C), methanol, and DMSO (<1 mg/ml at 25° C) |
存贮条件 | 储存温度2-8℃ |
密度 | 1.2000 |
应用 | It is used as an antirheumatic and as a chelating agent in Wilson′s disease. It is used as a copper chelator to form mixed disulfides with cysteine or other sulfide media components. It is used to inactivate protein-1 DNA binding and to inhibit the growth of asynchronous cultures of rabbit articular chondrocytes. |
产品介绍 | Penicillamine is an exogenous NOS modulator, found to inhibit urease activity. |
生化机理 | Penicillamine is a characteristic degradation product of penicillin type antibiotics. One atom of copper combines with two molecules of penicillamine. Penicillamine reduces excess cystine excretion in cystinuria. This is by disulfide interchange between penicillamine and cystine, which results in formation of a readily excreted penicillamine-cysteine disulfide. Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. Penicillamine lowers IgM rheumatoid factor and depresses T-cell activity. |
别名 | 3,3-二甲基-D-半胱氨酸; 3-巯基-D-缬氨酸; D-(-)-2-氨基-3-巯基-3-甲基丁酸; 二甲基半胱胺酸; β-巯基缬氨酸; D-(-)-青霉胺;Cuprimine; 3-Mercapto-D-valine; Mercaptovaline; Penicillamine; D-β,β-Dimethylcysteine; D-(?)-2-Amino-3-mercapto-3-methylbutanoic acid; D-β-Mercaptovaline;3,3-Dimethyl-D-cysteine |
D-青霉胺
D-Penicillamine (订货以英文为准)
编号:P115952
CAS号:52-67-5
分子式:C5H11NO2S
分子量:149.21
产品名称 | D-Penicillamine |
中文名称 | D-青霉胺 |
CAS号 | 52-67-5 |
MDL编码 | MFCD00064302 |
分子式(M.F.) | C5H11NO2S |
分子量(M.W.) | 149.21 |
储存条件 | 2-8°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs06.jpg |
信号词 | Danger |
危害声明 | H301,H310,H315,H319,H335 |
警示性声明 | P261,P280,P302+P350,P305+P351+P338,P310 |
个人防护设备 | Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges |
RTECS | LV2500000 |
WGK德国 | 3 |
风险声明 (欧洲) | R21;R25;R36/37/38; |
安全声明(欧洲) | S36/37/39/;S45; |
危害码(欧洲) | T |
UN代码 | 3462 |
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