溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
生化机理 | The attenuating effect of AZD7687, the selective DGAT1 inhibitor, on postprandial triacylglycerol (TAG) excursion provides proof of mechanism with respect to gut DGAT1 inhibition. Nausea, vomiting and diarrhoea were reported with increasing doses and they limited dose escalation. Lowering of SMM fat content to 45 or 30% in five cohorts gradually reduced the frequency of gastrointestinal symptoms at a given dose of AZD7687. |
AZD7687,DGAT1抑制剂
AZD7687 (订货以英文为准)
编号:A128057
CAS号:1166827-44-6
分子式:C21H25N3O3
分子量:367.44
产品名称 | AZD7687 |
中文名称 | AZD7687,DGAT1抑制剂 |
CAS号 | 1166827-44-6 |
分子式(M.F.) | C21H25N3O3 |
分子量(M.W.) | 367.44 |
储存条件 | -20°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs06.jpg |
信号词 | Danger |
危害声明 | H301 |
警示性声明 | P301 + P310 |
WGK德国 | 3 |
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