溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
产品介绍 | DMAT 是一种有效的,特异性的 CK2 抑制剂,IC50 值为 130 nM |
生化机理 | Casein kinase II inhibitor II (Ck2 Inhibitor II) is a high affinity ATP-competitive inhibitor of casein kinase II. Ck2 Inhibitor II inhibits CK2 in rat liver with 1,300-fold greater selectivity for CK2 than for CK1 (IC50 = 140 nM and >200 μM respectively). Ki = 40 nM; In Jurkat human T-cell leukemia cells, Ck2 Inhibitor II does not display side effects on mitochondria polarization at concentrations up to 10 μM; Ck2 Inhibitor II is useful for in vivo studies due to cell permeability and high efficacy in cultured cells and has implications in research and treatment of neoplasia and infective diseases, in which CK2 plays a role and is highly active constitutively. |
别名 | 2-二甲基氨基-4,5,6,7-四溴苯并咪唑;Casein kinase II Inhibitor;CK2 Inhibitor;CK2 Inhibitor II; 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole;4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine;4,5,6,7-Tetrabromo-N,N-dimethyl-1H-benzo[d]imidazol-2-amine; |
2-二甲基氨基-4,5,6,7-四溴苯并咪唑(DMAT)
DMAT (订货以英文为准)
编号:D127353
CAS号:749234-11-5
分子式:C9H7BR4N3
分子量:476.79
产品名称 | DMAT |
中文名称 | 2-二甲基氨基-4,5,6,7-四溴苯并咪唑(DMAT) |
CAS号 | 749234-11-5 |
分子式(M.F.) | C9H7BR4N3 |
分子量(M.W.) | 476.79 |
储存条件 | -20°C储存 |
技术规格
Background: | May be involved in meiosis or the maturation of germ cells. |
Applications: | ELISA, IHC |
Name of antibody: | OSGIN2 |
Immunogen: | Fusion protein of human OSGIN2 |
Full name: | oxidative stress induced growth inhibitor family member 2 |
Synonyms: | hT41; C8orf1 |
SwissProt: | Q9Y236 |
ELISA Recommended dilution: | 5000-10000 |
IHC positive control: | Human gastric cancer and Human tonsil |
IHC Recommend dilution: | 50-200 |
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