溶解性 | DMSO 104 mg/mL Water <1 mg/mL Ethanol 5 mg/mL |
存贮条件 | 储存温度-20°C |
备注 | PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2. |
生化机理 | PF-04929113 is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM. |
别名 | (1r,4r)-4-(2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl)phenylamino)cyclohexyl 2-aminoacetate;(1r,4r)-4-(2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydroindazol-1-yl)phenylamino)cyclohexyl 2-aminoacetate |
PF-04929113(SNX-5422),Hsp90抑制剂
PF-04929113 (SNX-5422) (订货以英文为准)
编号:P126273
CAS号:908115-27-5
分子式:C25H30F3N5O4
分子量:521.53
产品名称 | PF-04929113 (SNX-5422) |
中文名称 | PF-04929113(SNX-5422),Hsp90抑制剂 |
CAS号 | 908115-27-5 |
分子式(M.F.) | C25H30F3N5O4 |
分子量(M.W.) | 521.53 |
储存条件 | -20°C储存 |
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