溶解性 | DMSO 72 mg/mL Water <1 mg/mL Ethanol 11 mg/mL |
存贮条件 | 储存温度-20°C |
产品介绍 | A-803467 |
备注 | A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents, exhibits >100-fold selectivity against human NaV1.2, NaV1.3, NaV1.5, and NaV1.7. |
生化机理 | A 803467 is a selective Nav1.8 sodium channel blocker and analgesic. A 803467 blocks Nav1.8 with an IC50 of 8 nM and is over 100-fold more selective vs. human Nav1.2, 1.3, 1.5 and 1.7. A 803467 dose-dependently reduces behavioral responses in a variety of neuropathic and inflammatory pain models. |
别名 | 5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide;5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide |
A-803467,Na V 1.8通道阻滞剂
A-803467 (订货以英文为准)
编号:A127941
CAS号:944261-79-4
分子式:C19H16CLNO4
分子量:357.79
产品名称 | A-803467 |
中文名称 | A-803467,Na V 1.8通道阻滞剂 |
CAS号 | 944261-79-4 |
MDL编码 | MFCD10574689 |
分子式(M.F.) | C19H16CLNO4 |
分子量(M.W.) | 357.79 |
储存条件 | -20°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg |
信号词 | Warning |
危害声明 | H315-H319-H335 |
警示性声明 | P261-P305 + P351 + P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
RTECS | DD9487500 |
WGK德国 | 2 |
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