A-803467,Na V 1.8通道阻滞剂

A-803467 (订货以英文为准)

编号:A127941
CAS号:944261-79-4
分子式:C19H16CLNO4
分子量:357.79
货号 品牌 包装 目录价 您的价格 库存 数量 购买
A127941-10mg 阿拉丁 10mg ¥458.90
A127941-50mg 阿拉丁 50mg ¥1536.90
产品名称 A-803467
中文名称 A-803467,Na V 1.8通道阻滞剂
CAS号 944261-79-4
MDL编码 MFCD10574689
分子式(M.F.) C19H16CLNO4
分子量(M.W.) 357.79
储存条件 -20°C储存
溶解性DMSO 72 mg/mL Water <1 mg/mL Ethanol 11 mg/mL
存贮条件储存温度-20°C
产品介绍A-803467
备注A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents, exhibits >100-fold selectivity against human NaV1.2, NaV1.3, NaV1.5, and NaV1.7.
生化机理A 803467 is a selective Nav1.8 sodium channel blocker and analgesic. A 803467 blocks Nav1.8 with an IC50 of 8 nM and is over 100-fold more selective vs. human Nav1.2, 1.3, 1.5 and 1.7. A 803467 dose-dependently reduces behavioral responses in a variety of neuropathic and inflammatory pain models.
别名5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide;5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
标识符号https://www.aladdin-e.com/images/ghs/ghs07.jpg
信号词Warning
危害声明H315-H319-H335
警示性声明P261-P305 + P351 + P338
个人防护设备dust mask type N95 (US), Eyeshields, Gloves
RTECSDD9487500
WGK德国2
搜索质检报告(COA)
搜索MSDS
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