VULM 1457,γ分泌酶抑制剂

Avagacestat (订货以英文为准)

编号:B126453
CAS号:1146699-66-2
分子式:C20H17CLF4N4O4S
分子量:520.89
货号 品牌 包装 目录价 您的价格 库存 数量 购买
B126453-50mg 阿拉丁 50mg ¥2987.90
B126453-5mg 阿拉丁 5mg ¥589.90
B126453-10mg 阿拉丁 10mg ¥763.90
B126453-1mg 阿拉丁 1mg ¥469.90
产品名称 Avagacestat
中文名称 VULM 1457,γ分泌酶抑制剂
CAS号 1146699-66-2
分子式(M.F.) C20H17CLF4N4O4S
分子量(M.W.) 520.89
储存条件 -20°C储存
溶解性DMSO 104 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
存贮条件储存温度-20°C
备注BMS-708163 is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
生化机理BMS-708163 is a γ-secretase inhibitor (GSI) (IC50 =0.3 nM)
别名(2R)-2-(N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-4-chlorophenylsulfonamido)-5,5,5-trifluoropentanamide;(2R)-2-(N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-4-chlorophenylsulfonamido)-5,5,5-trifluoropentanamide
搜索质检报告(COA)
搜索MSDS
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