About this protein | |
Product name | ACTH(1-39) human (人促肾上腺皮质激素, 1-39) |
Alternative names | Adrenocorticotropic Hormone 1-39, human;Corticotropin |
Description | Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a cleavage product from a larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal cortex by acting through a cell membrane receptor (ACTH-R). In mammals, the action of ACTH is limited to those areas of the adrenal cortex in which the glucocorticoid hormones cortisol (hydrocortisone) and corticosterone are formed. ACTH has little control over the secretion of aldosterone, the other major steroid hormone from the adrenal cortex. |
Purity | >95%(HPLC) |
CAS Number | 12279-41-3 |
Molecular Formula | C207H308N56O58S |
Molecular Weight | 4541.1 |
Sequence (Three-Letter Code) |
Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe |
Sequence (One-Letter Code) |
SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF |
Source | Synthetic |
Reconstitution | Dissolve in distilled water or DMSO |
包装清单:
产品编号 | 产品名称 | 包装 |
P9023-1mg | ACTH(1-39) human (人促肾上腺皮质激素, 1-39) | 1mg |
P9023-5mg | ACTH(1-39) human (人促肾上腺皮质激素, 1-39) | 5mg |
P9023-25mg | ACTH(1-39) human (人促肾上腺皮质激素, 1-39) | 25mg |
— | 说明书 | 1份 |
保存条件:
-20℃或更低温度保存,至少一年有效。由于多肽的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
本产品为冻干粉,由于微量的多肽在冻干过程中沉积在管内,形成很薄或不可见的多肽层,所以在打开管盖前,我们建议在离心机中约8,000-12,000g离心10-30秒,使附着在管盖或管壁上的多肽聚集于管底。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。