重组人5-formyltetrahydrofolate cyclo-ligase, C-6His, E.coli

产品编号:C521533 品牌:生工
产品特点:
货号 包装 规格 目录价 您的价格 库存 数量 购买
C521533-0010 10UG ¥1260.00
C521533-0050 50UG ¥3696.00

概述

Recombinant Human 5-formyltetrahydrofolate Cyclo-ligase is produced by our E.coli expression system and the target gene encoding Met1-Ala203 is expressed with a 6His tag at the C-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

技术规格

Tag C-6His
种属 Human
表达系统 E.coli
Accession# P49914
Source E.coli
Formulation_Description Supplied as a 0.2 μm filtered solution of 20mM Tris, 200mM Nacl, 1mM DTT, 50% Glycerol, pH 8.0.
Storage Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
Purity Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background 5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion.
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