溶解性 | DMSO 83 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度-20°C |
备注 | PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity for B-RafV600E than wild-type B-Raf. |
生化机理 | PLX-4720 is a B-raf inhibitor with IC50 of 160 nM. |
别名 | N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide;N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide |
PLX-4720,B-Raf抑制剂
PLX-4720 (订货以英文为准)
编号:P127903
CAS号:918505-84-7
产品名称 | PLX-4720 |
中文名称 | PLX-4720,B-Raf抑制剂 |
CAS号 | 918505-84-7 |
储存条件 | -20°C储存 |
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