兔抗ABCC2多克隆抗体
产品编号：D152835
品牌：BBI
产品特点：
| 货号 | 包装 | 规格 | 目录价 | 您的价格 | 库存 | 数量 | 购买 |
|---|---|---|---|---|---|---|---|
| D152835-0025 | 25ul | ¥680.00 |
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| D152835-0200 | 200ul | ¥2500.00 |
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| D152835-0100 | 100ul | ¥1500.00 |
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技术规格
| Background: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. |
| Applications: | WB |
| Name of antibody: | ABCC2 |
| Immunogen: | Synthesized peptide derived from internal of human ABCC2. |
| Full name: | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| Synonyms： | DJS; MRP2; cMRP; ABC30; CMOAT |
| SwissProt: | Q92887 |
| WB Predicted band size: | 174 kDa |
| WB Positive control: | RAW264.7 cells lysate |
| WB Recommended dilution: | 500-3000 |
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