概述
Fusion protein corresponding to a region derived from 20-284 amino acids of human AMBP
技术规格
Full name: | alpha-1-microglobulin/bikunin precursor |
Synonyms: | A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC |
Swissprot: | P02760 |
Gene Accession: | BC041593 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. |