| 溶解性 | DMSO 104 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | GW5074 |
| 合法信息 | Sold for only research purposes |
| 备注 | GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. |
| 生化机理 | GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor (IC50 = 9 nM). GW 5074 displays ≥ 100-fold selectivity for raf kinase over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. |
| 别名 | 2H-Indol-2-one, 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-;2H-Indol-2-one, 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo- |
GW5074,c-Raf1激酶抑制剂
GW5074 （订货以英文为准）
编号：G129612
CAS号：220904-83-6
| 产品名称 | GW5074 |
| 中文名称 | GW5074,c-Raf1激酶抑制剂 |
| CAS号 | 220904-83-6 |
| MDL编码 | MFCD03453076 |
| 储存条件 | -20°C储存 |
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