溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
产品介绍 | Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. |
生化机理 | Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. |
别名 | RC-1291;ONO-7643;RC1291;ONO7643;RC 1291;ONO 7643;阿拉莫林; (3R)-1-(2-甲基丙氨酰-D-色氨酰)-3-苯甲基-3-哌啶 1,2,2-三甲基甲酰肼;RC-1291;ONO-7643;RC1291;ONO7643;RC 1291;ONO 7643;(3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide |
阿拉莫林
Anamorelin (订货以英文为准)
编号:A125440
CAS号:249921-19-5
分子式:C31H42N6O3
分子量:546.70
产品名称 | Anamorelin |
中文名称 | 阿拉莫林 |
CAS号 | 249921-19-5 |
分子式(M.F.) | C31H42N6O3 |
分子量(M.W.) | 546.70 |
储存条件 | -20°C储存 |
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