| 溶解性 | Soluble in DMSO (>10 mg/ml), DMF (~14 mg/ml), 1:1 solution of DMF: PBS (pH=7.2) (~0.5 mg/ml), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | 5,6-dimethylxanthenone-4-acetic acid (DMXAA) has been used to induce type-I IFN signaling in a stimulator of interferon genes (STING) dependent manner.It has also been used to study STING-dependent signaling in the absence of infection. |
| 产品介绍 | 5,6-dimethylxanthenone-4-acetic acid (DMXAA) is a flavone acetic acid derivative. It acts as a vascular disrupting agent (VDA), which damages tumor vasculature and stimulates an anti-tumor immune response. It stimulates hemorrhagic necrosis. |
| 备注 | DMXAA (Vadimezan) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM, respectively. Phase 3. |
| 生化机理 | DMXAA is an apoptosis inducer, and an anti-vascular. DMXAA is an inhibitor of NQO1, Flk-1 and Flt-1. |
| 别名 | ASA404; 5,6-MeXAA; NSC-640488;2,5-己酮可可碱; 5,6-二甲基呫吨酮-4-乙酸; 5,6-二甲基黄嘌呤-4-乙酸;5,6-Dimethylxanthenone-4-acetic Acid; ASA404; Vadimezan;5,6-MeXAA; NSC-640488 |
DMXAA (Vadimezan),血管破坏剂
DMXAA (Vadimezan) （订货以英文为准）
编号：D129922
CAS号：117570-53-3
分子式：C17H14O4
分子量：282.29
| 产品名称 | DMXAA (Vadimezan) |
| 中文名称 | DMXAA (Vadimezan),血管破坏剂 |
| CAS号 | 117570-53-3 |
| 分子式（M.F.） | C17H14O4 |
| 分子量（M.W.） | 282.29 |
| 储存条件 | 2-8°C储存 |
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