溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
生化机理 | Description:IC50 Value: N/AZaltidine is a H2-receptor antagonist, which has the antisecretory action.in vitro: N/Ain vivo: In eight healthy male volunteers single oral doses of 5 mg, 25 mg and 100 mg produced dose-related inhibition of basal and pentagastrin-stimulated acid output (M.A.O.) with an estimated ID50 of 40 mg for the latter. In eight subjects with duodenal ulceration single 100 mg and 200 mg doses produced 85% and 97% inhibition of M.A.O. at peak (3 h post-dose) and 20% and 23% inhibition at 24 h, respectively; inhibition of basal acid output was 97% at 3 h and 50% at 24 h with both doses [1]. One hundred and thirty-five patients were randomly allocated to 4 weeks' treatment with either 150 mg zaltidine once daily or placebo. Fifty-nine were treated for a full 4 weeks with zaltidine before the trial was stopped. Healing rates after 4 weeks of zaltidine and placebo were 86% and 19%, respectively (p less than 0.001) [2].Clinical trial: N/A |
唑替丁
Zaltidine (订货以英文为准)
编号:Z127855
CAS号:85604-00-8
分子式:C8H10N6S
分子量:222.27
产品名称 | Zaltidine |
中文名称 | 唑替丁 |
CAS号 | 85604-00-8 |
分子式(M.F.) | C8H10N6S |
分子量(M.W.) | 222.27 |
储存条件 | -20°C储存 |
标识符号 | https://www.aladdin-e.com/images/ghs/ghs07.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg |
信号词 | Warning |
危害声明 | H302-H351 |
警示性声明 | P281 |
个人防护设备 | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
RTECS | DP3750000 |
WGK德国 | 3 |
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