| 溶解性 | DMSO 129 mg/mL Water <1 mg/mL Ethanol <1 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 备注 | Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM, reverses drug resistance in MDR cell Lines. Phase 3. |
| 生化机理 | Tariquidar is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. |
| 别名 | 3-Quinolinecarboxamide, N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-;3-Quinolinecarboxamide, N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]- |
他立喹达
Tariquidar （订货以英文为准）
编号：T126671
CAS号：206873-63-4
分子式：C38H38N4O6
分子量：646.73
| 产品名称 | Tariquidar |
| 中文名称 | 他立喹达 |
| CAS号 | 206873-63-4 |
| 分子式（M.F.） | C38H38N4O6 |
| 分子量（M.W.） | 646.73 |
| 储存条件 | -20°C储存 |
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