组胺

Histamine, Free Base (订货以英文为准)

编号:H111796
CAS号:51-45-6
货号 品牌 包装 目录价 您的价格 库存 数量 购买
H111796-5g 阿拉丁 5g ¥1194.90
H111796-1g 阿拉丁 1g ¥285.90
H111796-250mg 阿拉丁 250mg ¥100.90
056045-013 250mg ¥100.90
056045-009 5g ¥1194.90
056045-010 200mg ¥95.90
056045-011 1g ¥285.90
产品名称 Histamine, Free Base
中文名称 组胺
CAS号 51-45-6
储存条件 避光;-20°C储存;充氩
沸点167°C
熔点83-84°C
敏感性易吸潮,对热和光敏感
溶解性Soluble in water, alcohol, and hot chloroform.
存贮条件储存温度-20°C
密度1.1400
应用内源性H1 和 H2 组胺受体激动剂;H1 激活并使Ca2+移动;H2 激活并刺激神经元中腺苷酸环化酶(adenylate cyclase)活性;激活NO合成酶;血管扩张剂。
产品介绍有吸湿性。在日光下易变质。组胺由组氨酸脱羧基形成,广泛分布在哺乳动物的组织中,尤其在肥大细胞及有关嗜碱性白细胞内(在变态反应中肥大细胞释放出组胺)。可以组氨酚为原料发酵制得。
生化机理Histamine, Free Base is a potent vasodilator found in normal tissues and blood. This compound is formed by the decarboxylation of L-histidine and activates NOS (nitric oxide synthase), resulting in the release of nitric oxide. Activation of Histamine H1 Receptors leads to Ca2+ mobilization; whereas, Histamine H2 Receptor activation stimulates adenylate cyclase activity in neurons. Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation.
别名β-氨乙基咪唑;1H-咪唑-4-乙胺;2-(4-咪唑基)乙胺;2-(4-Imidazolyl)ethylamine;1H-Imidazole-4-ethanamine; Ergotidine
标识符号https://www.aladdin-e.com/images/ghs/ghs06.jpg,https://www.aladdin-e.com/images/ghs/ghs08.jpg
信号词Danger
危害声明H301,H315,H317,H319,H334,H335
警示性声明P261,P280,P301+P310,P305+P351+P338,P342+P311
个人防护设备dust mask type N95 (US),Eyeshields,Faceshields,Gloves
RTECSMS1050000
WGK德国3
风险声明 (欧洲)22,36/37/38,42/43
安全声明(欧洲)22,26,36/37
危害码(欧洲)Xn
UN代码2811
搜索质检报告(COA)
搜索MSDS
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