| 溶解性 | DMSO ≥20mg/mL Water <1.2mg/mL Ethanol ≥11mg/mL |
| 存贮条件 | 储存温度 -20°C |
| 产品介绍 | AG14361是PARP1抑制剂，Ki<5 nM，比苯甲酰胺的抑制性强1000倍。 |
| 生化机理 | AG14361 is at least 1000-fold more potent than the benzamides.AG14361 treatment before irradiation statistically significantly increases the sensitivity to radiation therapy of mice bearing LoVo xenografts. AG14361 statistically significantly increases blood flow in xenografts and thus potentially increases drug delivery to tumor xenografts. |
| 别名 | AG 14361; 2-(4-((二甲基氨基)甲基)苯基)-5,6-二氢咪唑并(4,5,1-jk)(1,4)苯并二氮杂卓-7(4H)-酮;AG 14361; AG-14361;2-(4-((dimethylamino)methyl)phenyl)-5,6-dihydroimidazo(4,5,1-jk)(1,4)benzodiazepin-7(4h)-one; Imidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one |
AG14361
AG14361 （订货以英文为准）
编号：A125467
CAS号：328543-09-5
分子式：C19H20N4O
分子量：320.39
| 产品名称 | AG14361 |
| 中文名称 | AG14361 |
| CAS号 | 328543-09-5 |
| 分子式（M.F.） | C19H20N4O |
| 分子量（M.W.） | 320.39 |
| 储存条件 | -20°C储存 |
| 标识符号 | https://www.aladdin-e.com/images/ghs/ghs08.jpg |
| 信号词 | Warning |
| 危害声明 | H351 |
| 警示性声明 | P281 |
| 个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
| RTECS | TU5010000 |
| WGK德国 | 3 |
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