| 溶解性 | DMSO |
| 存贮条件 | 储存温度-20°C |
| 应用 | A P2X3 and P2X2/3 receptor antagonist |
| 产品介绍 | A-317491是非核苷酸类P2X3和P2X2/3受体拮抗剂，能抑制由其介导的钙流。 |
| 生化机理 | A-317491 is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors. It is known that P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Studies indicate that the P2X3 receptor is implicated in both neuropathic and inflammatory pain. P2X3 receptor is a promising target for therapeutic intervention in cancer patients for pain management. |
| 别名 | A 317491;A317491;A 317491;A317491; 5-[[(3-Phenoxybenzyl)[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]carbonyl]-1,2,4-benzenetricarboxylic acid |
A-317491,P2X3和P2X2/3受体拮抗剂
A-317491 （订货以英文为准）
编号：A126016
CAS号：475205-49-3
分子式：C33H27NO8
分子量：565.57
| 产品名称 | A-317491 |
| 中文名称 | A-317491,P2X3和P2X2/3受体拮抗剂 |
| CAS号 | 475205-49-3 |
| 分子式（M.F.） | C33H27NO8 |
| 分子量（M.W.） | 565.57 |
| 储存条件 | -20°C储存 |
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