藤黄酸

Gambogic acid (订货以英文为准)

编号:G101480
CAS号:2752-65-0
货号 品牌 包装 目录价 您的价格 库存 数量 购买
G101480-100mg 阿拉丁 100mg ¥1185.90
G101480-25mg 阿拉丁 25mg ¥429.90
G101480-5mg 阿拉丁 5mg ¥184.90
G101480-250mg 阿拉丁 250mg ¥1776.90
G101480-1mg 1mg ¥46.90
085273-014 100mg ¥1185.90
085273-010 5mg ¥184.90
085273-011 250mg ¥1776.90
085273-012 25mg ¥429.90
产品名称 Gambogic acid
中文名称 藤黄酸
CAS号 2752-65-0
储存条件 -20°C储存
沸点280°C
熔点81.8°C
溶解性DMSO: ≥100 mg/mL;H2O: insoluble;Ethanol:100 mg/mL
存贮条件储存温度-20°C
密度1.2900
应用藤黄酸作为蛋白酶激活和凋亡诱导剂,会捕获细胞周期的G2 / M期,而且造成不可逆。
产品介绍不溶于水
生化机理Gambogic acid is a xanthonoid that is derived from the brownish or orange resin from Garcinia hanburyi. This natural chemical has shown promising antitumor activity in clinical trials with mice. Gambogic Acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-xl, Bcl-2, Bcl-w, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47 μM, 1.21 μM, 2.02 μM, 0.66 μM, 1.06 μM and 0.79 μM, respectively. Gambogic acid acts as a caspase activator and apoptosis inducer, which causes an irreversible arrest in the G2/M phase of the cell cycle.
别名β-藤黄酸, 1,5-甲醇-1H,3H,11H-呋喃(3,4-g)吡喃(3,2-b)氧杂蒽-1-巴豆酸;B"-Guttiferrin Beta-Guttiferrin Beta-Guttilactone Cambogic acid Guttatic acid Guttic acid 1,51,5-Methano-1H,3H,11H-furo(3,4-G)pyrano(3,2-B)xanthene-1-crotonic acid
Merck Index4340
标识符号https://www.aladdin-e.com/images/ghs/ghs06.jpg
信号词Danger
危害声明H301
警示性声明P301+P310
个人防护设备Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges
RTECSDF8075000
WGK德国3
风险声明 (欧洲)25
安全声明(欧洲)45
危害码(欧洲)T
搜索质检报告(COA)
搜索MSDS
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