沸点 | 530.2 °C/760 mmHg |
溶解性 | DMSO ≥66mg/mL Water <1.2mg/mL Ethanol ≥4.6mg/mL |
存贮条件 | 储存温度-20°C |
密度 | 1.2000 |
应用 | A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3 |
产品介绍 | AT7867是ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂,IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM,对AGC激酶家族以外的蛋白几乎无活性。 |
备注 | AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family. |
生化机理 | AT7867 is a potent and oral AKT and p70 S6 kinase inhibitor with an IC50 of 17 nM. |
别名 | 4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶;pyrazole-based inhibitor 9;4-(4-Chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine |
4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶(AT7867)
AT7867 (订货以英文为准)
编号:A126209
CAS号:857531-00-1
分子式:C20H20CLN3
分子量:337.86
产品名称 | AT7867 |
中文名称 | 4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶(AT7867) |
CAS号 | 857531-00-1 |
分子式(M.F.) | C20H20CLN3 |
分子量(M.W.) | 337.86 |
储存条件 | -20°C储存 |
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